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Ensembles generated from crystal structures of single distant homologues solve challenging molecular-replacement cases in AMPLE

Molecular replacement (MR) is the predominant route to solution of the phase problem in macromolecular crystallography. Although routine in many cases, it becomes more effortful and often impossible when the available experimental structures typically used as search models are only distantly homolog...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Acta Crystallogr D Struct Biol
Κύριοι συγγραφείς: Rigden, Daniel J., Thomas, Jens M. H., Simkovic, Felix, Simpkin, Adam, Winn, Martyn D., Mayans, Olga, Keegan, Ronan M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: International Union of Crystallography 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947759/
https://ncbi.nlm.nih.gov/pubmed/29533226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798318002310
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