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Structural characterization of Porphyromonas gingivalis enoyl-ACP reductase II (FabK)

Enoyl-acyl carrier protein (ACP) reductase II (FabK) is a critical rate-limiting enzyme in the bacterial type II fatty-acid synthesis (FAS II) pathway. FAS II pathway enzymes are markedly disparate from their mammalian analogs in the FAS I pathway in both structure and mechanism. Enzymes involved in...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Hevener, Kirk E., Santarsiero, Bernard D., Lee, Hyun, Jones, Jesse A., Boci, Teuta, Johnson, Michael E., Mehboob, Shahila
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947681/
https://ncbi.nlm.nih.gov/pubmed/29400320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18000262
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