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Endoglin in human liver disease and murine models of liver fibrosis—A protective factor against liver fibrosis

BACKGROUND & AIMS: Liver fibrosis is the outcome of chronic liver injury. Transforming growth factor‐β (TGF‐β) is a major profibrogenic cytokine modulating hepatic stellate cell (HSC) activation and extracellular matrix homeostasis. This study analyses the effect of Endoglin (Eng), a TGF‐β type...

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Detalhes bibliográficos
Publicado no:Liver Int
Main Authors: Alsamman, Muhammad, Sterzer, Viktor, Meurer, Steffen K., Sahin, Hacer, Schaeper, Ute, Kuscuoglu, Deniz, Strnad, Pavel, Weiskirchen, Ralf, Trautwein, Christian, Scholten, David
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947658/
https://ncbi.nlm.nih.gov/pubmed/28941022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.13595
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