Overexpression of Endoglin Modulates TGF-β1-Signalling Pathways in a Novel Immortalized Mouse Hepatic Stellate Cell Line

Hepatic stellate cells (HSCs) play a major role in the pathogenesis of liver fibrosis. Working on primary HSCs requires difficult isolation procedures; therefore we have generated and here characterize a mouse hepatic stellate cell line expressing GFP under control of the collagen 1(I) promoter/enha...

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Main Authors: Meurer, Steffen K., Alsamman, Muhammad, Sahin, Hacer, Wasmuth, Hermann E., Kisseleva, Tatiana, Brenner, David A., Trautwein, Christian, Weiskirchen, Ralf, Scholten, David
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577806/
https://ncbi.nlm.nih.gov/pubmed/23437087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056116
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