Tumor Mutational Burden Guides Therapy in a Treatment Refractory POLE‐Mutant Uterine Carcinosarcoma

Gynecologic carcinosarcomas, previously known as malignant mixed Müllerian tumors, are uncommon malignancies that demonstrate an aggressive biology and lack a standard therapeutic approach. Molecular analyses have revealed recurrent alterations in chromatin remodeling genes, but clinical support for...

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Vydáno v:Oncologist
Hlavní autoři: Bhangoo, Munveer S., Boasberg, Peter, Mehta, Pareen, Elvin, Julia A., Ali, Siraj M., Wu, Winnie, Klempner, Samuel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: AlphaMed Press 2018
Témata:
Precision Medicine Clinic: Molecular Tumor Board
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947455/
https://ncbi.nlm.nih.gov/pubmed/29386312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0342
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