Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1‐linked amyotrophic lateral sclerosis mice

Cystatin C (CysC) is a major protein component of Bunina bodies, which are a pathological hallmark observed in the remaining motor neurons of patients with amyotrophic lateral sclerosis (ALS). Dominant mutations in the SOD1 gene, encoding Cu/Zn superoxide dismutase (SOD1), are causative for a subset...

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Bibliografiske detaljer
Udgivet i:J Neurochem
Main Authors: Watanabe, Seiji, Komine, Okiru, Endo, Fumito, Wakasugi, Keisuke, Yamanaka, Koji
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
ORIGINAL ARTICLES
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947136/
https://ncbi.nlm.nih.gov/pubmed/29282717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14285
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