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Chiron: translating nanopore raw signal directly into nucleotide sequence using deep learning

Sequencing by translocating DNA fragments through an array of nanopores is a rapidly maturing technology that offers faster and cheaper sequencing than other approaches. However, accurately deciphering the DNA sequence from the noisy and complex electrical signal is challenging. Here, we report Chir...

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Detalhes bibliográficos
Publicado no:Gigascience
Main Authors: Teng, Haotian, Cao, Minh Duc, Hall, Michael B, Duarte, Tania, Wang, Sheng, Coin, Lachlan J M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946831/
https://ncbi.nlm.nih.gov/pubmed/29648610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giy037
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