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Ongoing human chromosome end extension revealed by analysis of BioNano and nanopore data

The majority of human chromosome ends remain incompletely assembled due to their highly repetitive structure. In this study, we use BioNano data to anchor and extend chromosome ends from two European trios as well as two unrelated Asian genomes. At least 11 BioNano assembled chromosome ends are stru...

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Publicat a:Sci Rep
Autors principals: Shao, Haojing, Zhou, Chenxi, Cao, Minh Duc, Coin, Lachlan J. M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226469/
https://ncbi.nlm.nih.gov/pubmed/30413723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34774-0
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