Experimental sheep BSE prions generate the vCJD phenotype when serially passaged in transgenic mice expressing human prion protein

The epizootic prion disease of cattle, bovine spongiform encephalopathy (BSE), causes variant Creutzfeldt-Jakob disease (vCJD) in humans following dietary exposure. While it is assumed that all cases of vCJD attributed to a dietary aetiology are related to cattle BSE, sheep and goats are susceptible...

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Bibliografiska uppgifter
I publikationen:J Neurol Sci
Huvudupphovsmän: Joiner, Susan, Asante, Emmanuel A., Linehan, Jacqueline M., Brock, Lara, Brandner, Sebastian, Bellworthy, Susan J., Simmons, Marion M., Hope, James, Collinge, John, Wadsworth, Jonathan D.F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946165/
https://ncbi.nlm.nih.gov/pubmed/29406965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2017.12.038
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