Experimental sheep BSE prions generate the vCJD phenotype when serially passaged in transgenic mice expressing human prion protein

The epizootic prion disease of cattle, bovine spongiform encephalopathy (BSE), causes variant Creutzfeldt-Jakob disease (vCJD) in humans following dietary exposure. While it is assumed that all cases of vCJD attributed to a dietary aetiology are related to cattle BSE, sheep and goats are susceptible...

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Vydáno v:J Neurol Sci
Hlavní autoři: Joiner, Susan, Asante, Emmanuel A., Linehan, Jacqueline M., Brock, Lara, Brandner, Sebastian, Bellworthy, Susan J., Simmons, Marion M., Hope, James, Collinge, John, Wadsworth, Jonathan D.F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946165/
https://ncbi.nlm.nih.gov/pubmed/29406965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2017.12.038
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