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nNOS–CAPON interaction mediates amyloid‐β‐induced neurotoxicity, especially in the early stages
In neurons, increased protein–protein interactions between neuronal nitric oxide synthase (nNOS) and its carboxy‐terminal PDZ ligand (CAPON) contribute to excitotoxicity and abnormal dendritic spine development, both of which are involved in the development of Alzheimer's disease. In models of...
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| Publicado no: | Aging Cell |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5946066/ https://ncbi.nlm.nih.gov/pubmed/29577585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12754 |
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