Therapeutic Interference With Vascular Calcification—Lessons From Klotho-Hypomorphic Mice and Beyond

Medial vascular calcification, a major pathophysiological process associated with cardiovascular disease and mortality, involves osteo-/chondrogenic transdifferentiation of vascular smooth muscle cells (VSMCs). In chronic kidney disease (CKD), osteo-/chondrogenic transdifferentiation of VSMCs and, t...

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Detalles Bibliográficos
Publicado en:Front Endocrinol (Lausanne)
Autores principales: Lang, Florian, Leibrock, Christina, Pelzl, Lisann, Gawaz, Meinrad, Pieske, Burkert, Alesutan, Ioana, Voelkl, Jakob
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945862/
https://ncbi.nlm.nih.gov/pubmed/29780355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00207
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