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Spontaneous Hair Cell Regeneration Is Prevented by Increased Notch Signaling in Supporting Cells

During embryonic development, differentiation of cochlear progenitor cells into hair cells (HCs) or supporting cells (SCs) is partially controlled through Notch signaling. Many studies have shown that inhibition of Notch signaling allows SCs to convert into HCs in both normal and drug damaged neonat...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: McGovern, Melissa M., Zhou, Luyi, Randle, Michelle R., Cox, Brandon C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945818/
https://ncbi.nlm.nih.gov/pubmed/29780306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00120
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