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Endogenous hepcidin synthesis protects the distal nephron against hemin and hemoglobin mediated necroptosis
Hemoglobinuria is associated with kidney injury in various hemolytic pathologies. Currently, there is no treatment available and its pathophysiology is not completely understood. Here we studied the potential detrimental effects of hemoglobin (Hb) exposure to the distal nephron (DN). Involvement of...
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| Vydáno v: | Cell Death Dis |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5945780/ https://ncbi.nlm.nih.gov/pubmed/29749404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0568-z |
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