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Exploring DNA quality of single cells for genome analysis with simultaneous whole-genome amplification

Single cell genome analysis methods are powerful tools to define features of single cells and to identify differences between them. Since the DNA amount of a single cell is very limited, cellular DNA usually needs to be amplified by whole-genome amplification before being subjected to further analys...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Bäumer, Christiane, Fisch, Evelyn, Wedler, Holger, Reinecke, Frank, Korfhage, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945709/
https://ncbi.nlm.nih.gov/pubmed/29748573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25895-7
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