BH4 domain peptides derived from Bcl-2/Bcl-XL as novel tools against acute pancreatitis

Biliary acute pancreatitis (AP) is a serious condition, which currently has no specific treatment. Taurolithocholic acid 3-sulfate (TLC-S) is one of the most potent bile acids causing cytosolic Ca(2+) overload in pancreatic acinar cells (PACs), which results in premature activation of digestive enzy...

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Udgivet i:Cell Death Discov
Main Authors: Vervliet, Tim, Gerasimenko, Julia V., Ferdek, Pawel E., Jakubowska, Monika A., Petersen, Ole H., Gerasimenko, Oleg V., Bultynck, Geert
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945673/
https://ncbi.nlm.nih.gov/pubmed/29760956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0054-5
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