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Bile acids induce necrosis in pancreatic stellate cells dependent on calcium entry and sodium‐driven bile uptake
KEY POINTS: Acute biliary pancreatitis is a sudden and severe condition initiated by bile reflux into the pancreas. Bile acids are known to induce Ca(2+) signals and necrosis in isolated pancreatic acinar cells but the effects of bile acids on stellate cells are unexplored. Here we show that cholate...
Zapisane w:
| Wydane w: | J Physiol |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
John Wiley and Sons Inc.
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5088250/ https://ncbi.nlm.nih.gov/pubmed/27406326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272774 |
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