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MiR-455-3p inhibits the degenerate process of chondrogenic differentiation through modification of DNA methylation

The aim of this work was to determine whether miR-455-3p regulates DNA methylation during chondrogenic differentiation of hMSCs. The expression of miR-455-3p and de novo methyltransferase DNMT3A was assessed in micromass culture of hBMSCs, which induced chondrogenic differentiation in vitro, and in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Sun, Hao, Zhao, Xiaoyi, Zhang, Chengyun, Zhang, Ziji, Lun, Jiayong, Liao, Weiming, Zhang, Zhiqi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945650/
https://ncbi.nlm.nih.gov/pubmed/29748607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0565-2
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