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TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression
TGF-β/Activin induces epithelial-to-mesenchymal transition and stemness in pancreatic ductal adenocarcinoma (PDAC). However, the microRNAs (miRNAs) regulated during this response have remained yet undetermined. Here, we show that TGF-β transcriptionally induces MIR100HG lncRNA, containing miR-100, m...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5945639/ https://ncbi.nlm.nih.gov/pubmed/29748571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03962-x |
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