TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression

TGF-β/Activin induces epithelial-to-mesenchymal transition and stemness in pancreatic ductal adenocarcinoma (PDAC). However, the microRNAs (miRNAs) regulated during this response have remained yet undetermined. Here, we show that TGF-β transcriptionally induces MIR100HG lncRNA, containing miR-100, m...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ottaviani, Silvia, Stebbing, Justin, Frampton, Adam E., Zagorac, Sladjana, Krell, Jonathan, de Giorgio, Alexander, Trabulo, Sara M., Nguyen, Van T. M., Magnani, Luca, Feng, Hugang, Giovannetti, Elisa, Funel, Niccola, Gress, Thomas M., Jiao, Long R., Lombardo, Ylenia, Lemoine, Nicholas R., Heeschen, Christopher, Castellano, Leandro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945639/
https://ncbi.nlm.nih.gov/pubmed/29748571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03962-x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados