CUL5 is required for thalidomide-dependent inhibition of cellular proliferation

Angiogenesis is essential for cancer metastasis, thus the discovery and characterization of molecules that inhibit this process is important. Thalidomide is a teratogenic drug which is known to inhibit angiogenesis and effectively inhibit cancer metastasis, yet the specific cellular targets for its...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Kunkler, Bryan, Salamango, Daniel, DeBruine, Zachary J., Ploch, Caitlin, Dean, Shirley, Grossens, David, Hledin, Michael P., Marquez, Gabriel A., Madden, Julie, Schnell, Abigayle, Short, Michael, Burnatowska-Hledin, Maria A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944951/
https://ncbi.nlm.nih.gov/pubmed/29746508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196760
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