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An ambient temperature-stable antitoxin of nine co-formulated antibodies for botulism caused by serotypes A, B and E

Safe and effective antitoxins to treat and prevent botulism are needed for biodefense. We have developed recombinant antibody-based therapeutics for botulinum neurotoxin (BoNT) serotypes A, B, and E. The mechanism of action of this antitoxin requires that three mAbs bind one toxin molecule to achiev...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Li, Mingxiang, Lee, Dennis, Obi, Chidi R., Freeberg, Joel K., Farr-Jones, Shauna, Tomic, Milan T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944936/
https://ncbi.nlm.nih.gov/pubmed/29746518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197011
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