Antibody-induced nonapoptotic cell death in human lymphoma and leukemia cells is mediated through a novel reactive oxygen species-dependent pathway

Monoclonal antibodies (mAbs) have revolutionized the treatment of B-cell malignancies. Although Fc-dependent mechanisms of mAb-mediated tumor clearance have been extensively studied, the ability of mAbs to directly evoke programmed cell death (PCD) in the target cell and the underlying mechanisms in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood
Principais autores: Honeychurch, Jamie, Alduaij, Waleed, Azizyan, Mahsa, Cheadle, Eleanor J., Pelicano, Helene, Ivanov, Andrei, Huang, Peng, Cragg, Mark S., Illidge, Tim M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944831/
https://ncbi.nlm.nih.gov/pubmed/22354003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-395541
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados