PRC1 fine-tunes gene repression and activation to safeguard skin development and stem cell specification

Polycomb repressive complexes (PRC) 1 and 2 are essential chromatin regulators of cell identity. PRC1, a dominant executer of Polycomb-mediated control, functions as multiple sub-complexes that possess catalytic-dependent H2AK119 mono-ubiquitination (H2AK119ub) and catalytic-independent activities....

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Bibliografski detalji
Izdano u:Cell Stem Cell
Glavni autori: Cohen, Idan, Zhao, Dejian, Bar, Carmit, Valdes, Victor J., Dauber-Decker, Katherine L., Nguyen, Minh Binh, Nakayama, Manabu, Rendl, Michael, Bickmore, Wendy A., Koseki, Haruhiko, Zheng, Deyou, Ezhkova, Elena
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944606/
https://ncbi.nlm.nih.gov/pubmed/29727681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.04.005
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