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Non-viral delivery systems for CRISPR/Cas9-based genome editing: challenges and opportunities

In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas (CRISPR-associated) genome editing systems have become one of the most robust platforms in basic biomedical research and therapeutic applications. To date, efficient in vivo delivery of the CRISPR/Cas9 system to t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomaterials
Hauptverfasser: Li, Ling, Hu, Shuo, Chen, Xiaoyuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944364/
https://ncbi.nlm.nih.gov/pubmed/29704747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.04.031
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