Resveratrol Inhibits ROS-Promoted Activation and Glycolysis of Pancreatic Stellate Cells via Suppression of miR-21

Activation of pancreatic stellate cells (PSCs) initiates pancreatic fibrosis in chronic pancreatitis and furnishes a niche that enhances the malignancy of pancreatic cancer cells (PCCs) in pancreatic ductal adenocarcinoma (PDAC). Resveratrol (RSV), a natural polyphenol, exhibits potent antioxidant a...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Yan, Bin, Cheng, Liang, Jiang, Zhengdong, Chen, Ke, Zhou, Cancan, Sun, Liankang, Cao, Junyu, Qian, Weikun, Li, Jie, Shan, Tao, Lei, Jianjun, Ma, Qingyong, Ma, Jiguang
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944235/
https://ncbi.nlm.nih.gov/pubmed/29854071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/1346958
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