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Iron-catalyzed urea synthesis: dehydrogenative coupling of methanol and amines

Substituted ureas have numerous applications but their synthesis typically requires the use of highly toxic starting materials. Herein we describe the first base-metal catalyst for the selective synthesis of symmetric ureas via the dehydrogenative coupling of methanol with primary amines. Using a pi...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Lane, Elizabeth M., Hazari, Nilay, Bernskoetter, Wesley H.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944220/
https://ncbi.nlm.nih.gov/pubmed/29780531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc00775f
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