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Tumor Cell–Accelerated Senescence Is Associated With DNA-PKcs Status and Telomere Dysfunction Induced by Radiation

Whether telomere structure integrity is related to radiosensitivity is not well investigated thus far. In this study, we investigated the relation between telomere instability and radiation-induced accelerated senescence. Partial knockdown of DNA-dependent catalytic subunit of protein kinase (DNA-PK...

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Опубликовано в: :Dose Response
Главные авторы: Zhang, Miaomiao, Guo, Xiaopeng, Gao, Yue, Lu, Dong, Li, Wenjian
Формат: Artigo
Язык:Inglês
Опубликовано: SAGE Publications 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944147/
https://ncbi.nlm.nih.gov/pubmed/29760601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1559325818771527
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