Benefit, Risk, and Outcomes in Drug Development: A Systematic Review of Sunitinib

BACKGROUND: Little is known about the total patient burden associated with clinical development and where burdens fall most heavily during a drug development program. Our goal was to quantify the total patient burden/benefit in developing a new drug. METHODS: We measured risk using drug-related adve...

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Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Carlisle, Benjamin, Demko, Nadine, Freeman, Georgina, Hakala, Amanda, MacKinnon, Nathalie, Ramsay, Tim, Hey, Spencer, London, Alex John, Kimmelman, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943825/
https://ncbi.nlm.nih.gov/pubmed/26547927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv292
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