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Unsuccessful Trial Accrual and Human Subjects Protections: An Empirical Analysis of Recently Closed Trials

BACKGROUND: Ethical evaluation of risk/benefit in clinical trials is premised on the achievability of resolving research questions motivating an investigation. OBJECTIVE: To determine the fraction and number of patients enrolled in trials that were at risk of not meaningfully addressing their primar...

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Détails bibliographiques
Publié dans:Clin Trials
Auteurs principaux: Carlisle, Benjamin, Kimmelman, Jonathan, Ramsay, Tim, MacKinnon, Nathalie
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516407/
https://ncbi.nlm.nih.gov/pubmed/25475878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774514558307
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