Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection

Iron is an essential factor for the growth and virulence of Mycobacterium tuberculosis (Mtb). However, little is known about the mechanisms by which the host controls iron availability during infection. Since ferritin heavy chain (FtH) is a major intracellular source of reserve iron in the host, we...

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Bibliografski detalji
Izdano u:Front Immunol
Glavni autori: Reddy, Vineel P., Chinta, Krishna C., Saini, Vikram, Glasgow, Joel N., Hull, Travis D., Traylor, Amie, Rey-Stolle, Fernanda, Soares, Miguel P., Madansein, Rajhmun, Rahman, Md Aejazur, Barbas, Coral, Nargan, Kievershen, Naidoo, Threnesan, Ramdial, Pratistadevi K., George, James F., Agarwal, Anupam, Steyn, Adrie J. C.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Immunology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943674/
https://ncbi.nlm.nih.gov/pubmed/29774023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00860
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