Hypoxia/Reoxygenation of Rat Renal Arteries Impairs Vasorelaxation via Modulation of Endothelium-Independent sGC/cGMP/PKG Signaling

Ischemia/reperfusion injury holds a key position in many pathological conditions such as acute kidney injury and in the transition to chronic stages of renal damage. We hypothesized that besides a reported disproportional activation of vasoconstrictor response, hypoxia/reoxygenation (H/R) adversely...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Braun, Diana, Zollbrecht, Christa, Dietze, Stefanie, Schubert, Rudolf, Golz, Stefan, Summer, Holger, Persson, Pontus B., Carlström, Mattias, Ludwig, Marion, Patzak, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943512/
https://ncbi.nlm.nih.gov/pubmed/29773995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00480
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