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Trafficking, localization and degradation of the Na(+),HCO(3)(−) co-transporter NBCn1 in kidney and breast epithelial cells
The Na+;HCO3(−) co-transporter NBCn1 (SLC4A7) is a major regulator of intracellular pH yet its trafficking and turnover are essentially unstudied. Here, we used MDCK-II and MCF-7 cells to investigate these processes in epithelial cells. GFP-NBCn1 membrane localization was abolished by truncation of...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5943355/ https://ncbi.nlm.nih.gov/pubmed/29743600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25059-7 |
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