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Anomalous Scaling of Gene Expression in Confined Cell-Free Reactions

Cellular surface breaks the symmetry of molecular diffusion across membrane. Here, we study how steric interactions between the surface and the bulk of cell-sized emulsion droplets alters gene expression emulated by a cell-free transcription/translation (TXTL) system. The concentration of synthesize...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sakamoto, Ryota, Noireaux, Vincent, Maeda, Yusuke T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943292/
https://ncbi.nlm.nih.gov/pubmed/29743508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25532-3
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