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Blockade of BAFF Receptor BR3 on T cells Enhances Their Activation and Cytotoxicity

The BAFF receptor BR3 plays key roles in B cell activation, maturation, and survival whereas the function of BR3 on T lymphocytes is less well characterized. Previous reports have demonstrated that BR3 co-stimulates human T cell activation in vitro in the presence of high non-physiologic levels of p...

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Détails bibliographiques
Publié dans:J Immunother
Auteurs principaux: Bloom, Debra D., Reshetylo, Sofiya, Nytes, Cassandra, Goodsett, Claudia T, Hematti, Peiman
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943136/
https://ncbi.nlm.nih.gov/pubmed/29309290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000209
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