RosettaAntibodyDesign (RAbD): A general framework for computational antibody design

A structural-bioinformatics-based computational methodology and framework have been developed for the design of antibodies to targets of interest. RosettaAntibodyDesign (RAbD) samples the diverse sequence, structure, and binding space of an antibody to an antigen in highly customizable protocols for...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Adolf-Bryfogle, Jared, Kalyuzhniy, Oleks, Kubitz, Michael, Weitzner, Brian D., Hu, Xiaozhen, Adachi, Yumiko, Schief, William R., Dunbrack, Roland L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942852/
https://ncbi.nlm.nih.gov/pubmed/29702641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006112
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