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Modeling and docking antibody structures with Rosetta

We describe Rosetta-based computational protocols for predicting the three-dimensional structure of an antibody from sequence (RosettaAntibody) and then docking the antibody to protein antigens (SnugDock). Antibody modeling leverages canonical loop conformations to graft large segments from experime...

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Bibliografiska uppgifter
I publikationen:Nat Protoc
Huvudupphovsmän: Weitzner, Brian D., Jeliazkov, Jeliazko R., Lyskov, Sergey, Marze, Nicholas, Kuroda, Daisuke, Frick, Rahel, Adolf-Bryfogle, Jared, Biswas, Naireeta, Dunbrack, Roland L., Gray, Jeffrey J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739521/
https://ncbi.nlm.nih.gov/pubmed/28125104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.180
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