Characterization of SNF472 pharmacokinetics and efficacy in uremic and non-uremic rats models of cardiovascular calcification

End-stage renal disease is strongly associated with progressive cardiovascular calcification (CVC) and there is currently no therapy targeted to treat CVC. SNF472 is an experimental formulation under development for treatment of soft tissue calcification. We have investigated the pharmacokinetics of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ferrer, Miguel D., Ketteler, Markus, Tur, Fernando, Tur, Eva, Isern, Bernat, Salcedo, Carolina, Joubert, Pieter H., Behets, Geert J., Neven, Ellen, D’Haese, Patrick C., Perelló, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942814/
https://ncbi.nlm.nih.gov/pubmed/29742152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197061
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