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Active Maintenance of T Cell Memory in Acute and Chronic Viral Infection Depends on Continuous Expression of FOXO1

Immunity following an acutely resolved infection or the long-term equipoise of chronic viral infections often depends on the maintenance of antigen-specific CD8(+) T cells, yet the ongoing transcriptional requirements of these cells remain unclear. We show that active and continuous programming by F...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Utzschneider, Daniel T., Delpoux, Arnaud, Wieland, Dominik, Huang, Xin, Lai, Chen-Yen, Hofmann, Maike, Thimme, Robert, Hedrick, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942184/
https://ncbi.nlm.nih.gov/pubmed/29590615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.03.020
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