Multi-center phase II study of patupilone for recurrent or progressive brain metastases from non-small cell lung cancer

BACKGROUND: Treatment options for patients with non-small cell lung cancer (NSCLC) with brain metastases are limited. Patupilone (EPO906), a blood-brain barrier-penetrating, microtubule-targeting cytotoxic agent, has shown clinical activity in phase I/II studies in patients with NSCLC. This study ev...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Nayak, Lakshmi, DeAngelis, Lisa M., Robins, H. Ian, Govindan, Ramaswamy, Gadgeel, Shirish, Kelly, Karen, Rigas, James R., Peereboom, David M., Rosenfeld, Steven S., Muzikansky, Alona, Zheng, Ming, Urban, Patrick, Abrey, Lauren E., Omuro, Antonio, Wen, Patrick Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941922/
https://ncbi.nlm.nih.gov/pubmed/26308485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.29636
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