PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease. Part I: PPAR-α

This article provides a comprehensive review about the molecular and metabolic actions of PPAR-α. It describes its structural features, ligand specificity, gene transcription mechanisms, functional characteristics and target genes. In addition, recent progress with the use of loss of function and ga...

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Udgivet i:Future Cardiol
Main Authors: Han, Lu, Shen, Wen-Jun, Bittner, Stefanie, Kraemer, Fredric B, Azhar, Salman
Format: Artigo
Sprog:Inglês
Udgivet: Future Medicine Ltd 2017
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941715/
https://ncbi.nlm.nih.gov/pubmed/28581332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fca-2016-0059
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