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Integrative analyses of genes and microRNA expressions in human trisomy 21 placentas

BACKGROUND: The most frequent chromosomal aneuploidy is trisomy 21 (T21) that is caused by an extra copy of chromosome 21. The imbalance of whole genome including genes and microRNAs contributes to the various phenotypes of T21. However, the integrative association between genes and microRNAs in the...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Lim, Ji Hyae, Han, You Jung, Kim, Hyun Jin, Kim, Moon Young, Park, So Yeon, Cho, Youl-Hee, Ryu, Hyun Mee
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941645/
https://ncbi.nlm.nih.gov/pubmed/29739397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0361-y
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