Disease specific characteristics of fetal epigenetic markers for non-invasive prenatal testing of trisomy 21

BACKGROUND: Non-invasive prenatal testing of trisomy 21 (T21) is being actively investigated using fetal-specific epigenetic markers (EPs) that are present in maternal plasma. Recently, 12 EPs on chromosome 21 were identified based on tissue-specific epigenetic characteristics between placenta and b...

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Autores principales: Lim, Ji Hyae, Lee, Da Eun, Park, So Yeon, Kim, Do Jin, Ahn, Hyun Kyong, Han, You Jung, Kim, Moon Young, Ryu, Hyun Mee
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892082/
https://ncbi.nlm.nih.gov/pubmed/24397966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-7-1
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