DNA methylation in the APOE genomic region is associated with cognitive function in African Americans

BACKGROUND: Genetic variations in apolipoprotein E (APOE) and proximal genes (PVRL2, TOMM40, and APOC1) are associated with cognitive function and dementia, particularly Alzheimer’s disease. Epigenetic mechanisms such as DNA methylation play a central role in the regulation of gene expression. Recen...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Med Genomics
Main Authors: Liu, Jiaxuan, Zhao, Wei, Ware, Erin B., Turner, Stephen T., Mosley, Thomas H., Smith, Jennifer A.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941603/
https://ncbi.nlm.nih.gov/pubmed/29739406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0363-9
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki