Modeling the Causal Role of DNA Methylation in the Association Between Cigarette Smoking and Inflammation in African Americans: A 2-Step Epigenetic Mendelian Randomization Study

The association between cigarette smoking and inflammation is well known. However, the biological mechanisms behind the association are not fully understood, particularly the role of DNA methylation, which is known to be affected by smoking. Using 2-step epigenetic Mendelian randomization, we invest...

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Veröffentlicht in:Am J Epidemiol
Hauptverfasser: Jhun, Min A, Smith, Jennifer A, Ware, Erin B, Kardia, Sharon L R, Mosley, Thomas H, Turner, Stephen T, Peyser, Patricia A, Park, Sung Kyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860475/
https://ncbi.nlm.nih.gov/pubmed/29149250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwx181
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