Elevated serum RAS p21 is an independent prognostic factor in metastatic breast cancer

BACKGROUND: An important component of the RAS signalling pathway, the RAS p21 oncogene, is frequently hyperactivated in breast cancer. Its expression in tumor tissue has been linked to poor clinical outcome. This study was designed to evaluate the clinical relevance of RAS p21 levels in peripheral b...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Banys-Paluchowski, Malgorzata, Fehm, Tanja, Janni, Wolfgang, Aktas, Bahriye, Fasching, Peter A., Kasimir-Bauer, Sabine, Milde-Langosch, Karin, Pantel, Klaus, Rack, Brigitte, Riethdorf, Sabine, Solomayer, Erich-Franz, Witzel, Isabell, Müller, Volkmar
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941516/
https://ncbi.nlm.nih.gov/pubmed/29739347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4282-0
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