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The prognostic relevance of urokinase-type plasminogen activator (uPA) in the blood of patients with metastatic breast cancer

In breast cancer (BC), elevated levels of urokinase-type plasminogen activator (uPA) in tumor tissue have been confirmed as a strong prognostic factor in level-of-evidence-1 studies. The aim of the present study was to evaluate the clinical relevance of uPA levels in serum of metastatic BC patients...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Banys-Paluchowski, Malgorzata, Witzel, Isabell, Aktas, Bahriye, Fasching, Peter A., Hartkopf, Andreas, Janni, Wolfgang, Kasimir-Bauer, Sabine, Pantel, Klaus, Schön, Gerhard, Rack, Brigitte, Riethdorf, Sabine, Solomayer, Erich-Franz, Fehm, Tanja, Müller, Volkmar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381129/
https://ncbi.nlm.nih.gov/pubmed/30783124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37259-2
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