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Enhanced Solubilization of Class B Radical S-adenosylmethionine Methylases by Improved Cobalamin Uptake in Escherichia coli

The methylation of unactivated carbon and phosphorus centers is a burgeoning area of biological chemistry, especially given that such reactions constitute key steps in the biosynthesis of numerous enzyme cofactors, antibiotics, and other natural products of clinical value. These kinetically challeng...

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Библиографические подробности
Опубликовано в: :Biochemistry
Главные авторы: Lanz, Nicholas D., Blaszczyk, Anthony J., McCarthy, Erin L., Wang, Bo, Wang, Roy X., Jones, Brianne S., Booker, Squire J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941297/
https://ncbi.nlm.nih.gov/pubmed/29298049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01205
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