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Ancient thioredoxins evolved to modern-day stability–function requirement by altering native state ensemble
Thioredoxins (THRXs)—small globular proteins that reduce other proteins—are ubiquitous in all forms of life, from Archaea to mammals. Although ancestral thioredoxins share sequential and structural similarity with the modern-day (extant) homologues, they exhibit significantly different functional ac...
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| Publicado no: | Philos Trans R Soc Lond B Biol Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5941179/ https://ncbi.nlm.nih.gov/pubmed/29735738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2017.0184 |
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