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Exploration of genetic basis underlying individual differences in radiosensitivity within human populations using genome editing technology

DNA double-strand breaks (DSBs) induced by ionizing radiation (IR) are the initial and critical step in major alteration of genetic information and cell death. To prevent deleterious effects, DNA repair systems recognize and re-join DNA DSBs in human cells. It has been suggested that there are indiv...

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Podrobná bibliografie
Vydáno v:J Radiat Res
Hlavní autoři: Miyamoto, Tatsuo, Akutsu, Silvia Natsuko, Tauchi, Hiroshi, Kudo, Yoshiki, Tashiro, Satoshi, Yamamoto, Takashi, Matsuura, Shinya
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941146/
https://ncbi.nlm.nih.gov/pubmed/29528422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rry007
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