A High Frequency of HIV-Specific Circulating Follicular Helper T Cells Is Associated with Preserved Memory B Cell Responses in HIV Controllers

Follicular helper T cells (Tfh) play an essential role in the affinity maturation of the antibody response by providing help to B cells. To determine whether this CD4(+) T cell subset may contribute to the spontaneous control of HIV infection, we analyzed the phenotype and function of circulating Tf...

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Publicado en:mBio
Main Authors: Claireaux, M., Galperin, M., Benati, D., Nouël, A., Mukhopadhyay, M., Klingler, J., de Truchis, P., Zucman, D., Hendou, S., Boufassa, F., Moog, C., Lambotte, O., Chakrabarti, L. A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941072/
https://ncbi.nlm.nih.gov/pubmed/29739909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00317-18
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