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The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation

There is growing appreciation of the importance of the mechanical properties of the tumor microenvironment on disease progression. However, the role of extracellular matrix (ECM) stiffness and cellular mechanotransduction in epithelial ovarian cancer (EOC) is largely unknown. Here, we investigated t...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: McKenzie, Andrew J., Hicks, Stephanie R., Svec, Kathryn V., Naughton, Hannah, Edmunds, Zöe L., Howe, Alan K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940803/
https://ncbi.nlm.nih.gov/pubmed/29740072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25589-0
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